Amas de Casa Desesperadas is an Argentine television series, that debuted on Canal 13 on August 30, 2006. Set in the fictional Manzanares Street, a suburb surrounding Buenos Aires, the series follows the lives of four housewives and the domestic problems and daily mysteries surrounding their husbands, friends and neighbors, which can be more sinister than they appear. The series' tone combines elements of drama, comedy, mystery, farce, soap opera and satire.Based on the American television series, Desperate Housewives, it was developed for Argentina by Buena Vista International and Pol-Ka Producciones. The show’s first season was broadcast by Canal 13 on Argentina, and also by other networks on Uruguay and Paraguay. On October 2006, Canal 13 renewed Amas de Casa Desesperadas for a second season, that will start filming on August 2007.

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Florencia was raised with an absent mother and a father who rebuilt his life. Endure that reality with drugs and alcohol. Faced with her extreme behavior, her father sends her to her mother's house, where he will jeopardize his bond with her, but she will also meet Sebastián.

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Ernesto arrives in Buenos Aires from Germany, where he has lived since childhood, having been taken by his grandparents after his parents disappeared during the dictatorship. Now he has returned to the country that caused him so much harm, to take charge of the negotiations his grandfather's company maintained with Argentine firms until his recent death. As soon as he arrives in the country, fragments of a past he thought was lost return to his mind, and what was supposed to be a quick business transaction turns into an odyssey as he begins his search for a mysterious place and, unwittingly, for his own identity.

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Once again, the night sets in the city. Two young people look through faces on a phone, deciding and agreeing. ‘He's hot, him too.’ The decision is made before sunrise – a biology student with beautiful curly hair and shiny skin.

The relatives of those missing on Uritorco Hill travel to Capilla del Monte, Córdoba, to investigate the area in search of answers. With them are a parapsychologist, a UFO expert and a documentary filmmaker. In a mansion on the slopes, they have to fight for their lives, faced with the attack of the evil entity that returns to finish its disastrous work.